Links: Weeks of 27 Jun 2026
One Blood Test. Fifty Cancers. The Screening Revolution That Could Save Millions of Lives.
Cancer is now the number one killer of Americans over the age of 50. Not heart disease. Cancer. And the reason it kills so many isn’t that we can’t fight it. It’s that we don’t see it coming.
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Galleri captures cell-free DNA from a standard blood draw — a single vial — and sequences the methylation patterns across the genome using next-generation sequencing. An AI algorithm trained on massive datasets then analyzes these patterns to determine two things:
First, whether a cancer signal is present at all.
Second, where it’s likely coming from — which organ or tissue type is the probable source. This is called cancer signal origin prediction, and in studies, Galleri has achieved over 90% accuracy in identifying the tissue of origin.
The test result is not a diagnosis. It is a precision compass. It tells your physician: there is a cancer signal detected, and the predicted origin is your pancreas, or your lung, or your liver. Your physician then orders targeted follow-up imaging or biopsy to confirm or rule out the finding.
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A century ago, waterborne diseases levied similar costs to those posed by respiratory viruses like colds and influenza today: endemic, periodically epidemic, and widely accepted as an inevitable feature of human life. Then, at the turn of the twentieth century, we decided they didn’t have to be. Pharmaceutical advances and clean water infrastructure made cholera, typhoid, and dysentery rare across much of the world within a matter of decades.
Why haven’t we already seen the same kind of transformation with respiratory viruses?
Introducing Intercept, a $500M bet to make respiratory infections like colds and flu a thing of the past.
The boy from Bihar: The making of Vaibhav Sooryavanshi, Indian cricket’s 15-year-old batting prodigy
“When we took him to Patna for trials, in the whole area, the news spread that there was a small left-handed batter from Samastipur who had exceptional talent,” Jha says. “He was selected in the state Under-17 team at the age of eight-and-a-half.”
One of the most exciting stars in all sports.
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Over the past 12 months, the AI ecosystem generated $110 billion in revenue when you remove double-counting. The growth rate is healthy. Annualizing the most recent month’s revenues indicates a $175 billion revenue run rate. These revenues are growing faster than previous IT-oriented waves, roughly three times more rapidly than the mobile or Internet waves.